王家刚-山西农业大学农学院

姓名：王家刚

电子邮箱：wjg@sxau.edu.cn

通讯地址：山西省晋中市太谷区山西农业大学农学院

邮政编码：030801

一、个人简介

王家刚，男，1988年生，山东省临沂市人，现为山西农业大学农学院教授、三晋英才、博士生导师。

二、学习工作简历

学习简历：

2011.09-2016.06，山东农业大学，硕博连读，细胞生物学专业

2007.09-2011.06，山东农业大学，本科，生物技术专业

工作简历：

2021.01-至今，山西农业大学，校聘教授

2016.11-2020.12，山东大学，博士后

2016.06-2016.11，山东农业大学，研究助理

三、研究方向

1. 谷子氮高效分子机制研究

2. 谷子高产优质分子机制研究

四、教学科研概述

承担本科生《杂草学》等课程。长期从事谷子氮高效和高产优质的分子机制研究，先后主持国家、山西省、山东省和青岛市博士后等科学基金项目10余项，参加国家重大研究计划课题、国家自然科学基金等项目4项。在PNAS、Plant Cell、Plant Biotechnology Journal、Plant, Cell & Environment、Journal of Integrative Plant Biology、Journal of Integrative Agriculture、Plant Physiology等学术刊物发表论文30余篇。获得2019年度山东省高等学校科学技术奖叁等奖（第二完成人）和2020年度山东省科学技术奖二等奖（第三完成人）。

五、教学科研项目

1. 国家自然科学基金青年基金，逆境胁迫条件下谷子硝态氮转导的分子机制研究，主持；

2. 国家重点研发计划，杂粮作物种质资源精准鉴定与创新利用项目子课题-谷子高产优质种质资源的精准鉴定，主持；

3. 山西省后稷实验室自主立项课题5项，主持；

4. 三晋英才计划（科技创新领域青年拔尖人才），主持；

5. 山西农业大学高层次人才启动经费，主持；

6. 中国博士后科学基金第67批面上资助，HBI1-TCP20转录因子复合体正调控CEP1短肽介导系统氮需求的分子机制研究，主持；

7. 山东省博士后2020年度创新基金，HBI1通过调控硝态氮信号转导促进植物生长发育的分子机制研究，主持；

8. 2019年度青岛市博士后应用研究项目，主持；

9. 中国博士后科学基金第61批面上资助，赤霉素调控侧生生长点干细胞的起始和分化的分子机理研究，主持；

10. 山东省博士后2017年度创新基金，HBI1-HIC1转录因子复合体调控植物生长发育和免疫抗病平衡的分子机制研究，主持；

11. 中国博士后科学基金第11批特别资助，转录因子HBI1调控拟南芥不定根起始的分子机制研究，主持；

12. 国家重大研究计划课题，花粉管导向生长的分子网络，参加；

13. 国家自然科学基金面上项目，糖基磷脂酰肌醇锚定蛋白MDP在花粉管生长和导向过程中的作用机理研究，参加；

14. 国家自然科学基金面上项目，油菜素内酯和生物钟协调控制植物生长和免疫抗病平衡的分子机制，参加。

六、代表性论文

1.Zhang, L., Zhou, X., Hu, J., Wu, H., Yuan, X., Chu, X., & Wang, J. G. (2026). CRISPR/Cas9-mediated SiYABBY1 mutagenesis enhances cleistogamy and seed number and size in foxtail millet (Setaria italica). Journal of Integrative Agriculture, 0.

2.Zhao, R., Chen, J., Li, Y., Chen, D. Y., Kang, X., Dong, S., ... & Wang, J. G. (2026). CRISPR/Cas9-mediated α-prolamin gene (Seita. 8G190200) mutagenesis increases the content of functional amino acids in foxtail millet (Setaria italica). Plant Cell Reports, 45(3), 65.

3. Zhao, R., Chen, J., Li, Y., Jin, M., Liu, K., Liu, Y., ... & Wang, J. G. (2026). CRISPR/Cas9-mediated knockout of the 22 kDa α-prolamin genes orchestrates the regulation of functional amino acid content in foxtail millet. Journal of Plant Physiology, 154723.

4. Zhou, X., Zhang, L., Wu, H., Wang, H., Chen, J., Kang, X., ... Wang, J. G. & Chu, X. Q. (2026). CRISPR/Cas9-Mediated SiZAT12 Mutagenesis Enhances Drought Tolerance Without Yield Penalty in Foxtail Millet (Setaria italica). Plant Physiology and Biochemistry, 111096.

5. Chen, J., Zhang, Y., Zhao, R., Zhang, L., Zhou, X., Kang, X., ... & Wang, J. G. (2025). CRISPR/Cas9-Mediated Base Editing of SiGS1 Confers Glufosinate Resistance in Foxtail Millet (Setaria italica). Plant biotechnology journal.

6. Zhang, J. J., Zhang, M. H., Wu, H. J., Hu, J. X., Hao, J. H., Zhang, L. Q., ... & Wang, J. G. (2025). Transcriptome profiling of developing inflorescences reveals SiMADS1 as a key regulator of floral development in foxtail millet. Seed Biology, 4(1).

7. Zhang, L., Chen, J., Hao, J., Li, Z., Zhou, X., Hu, J., ... & Wang, J. G. (2025). Identification and characterization of burned inflorescence (buin) mutant in foxtail millet. Plant Growth Regulation, 105(6), 2231-2245.

8. Du, M., Zhang, F., Wang, X., Zhang, T., Yang, X., Liu, Y., ... & Wang, J. G. (2025). Structural and deleterious burdens and their effects on yield traits in foxtail millet domestication. iScience, 28(9).

9. Chu, X., Chen, D. Y., Sun, M., Zhang, J., Zhang, M., Wu, H., ... & Wang, J. G. (2025). Genome-Wide Identification of the SiNHX Gene Family in Foxtail Millet (Setaria Italica) and Functional Characterization of SiNHX7 in Arabidopsis. International Journal of Molecular Sciences, 26(15), 7139.

10. Kang, X., Hao, J. H., Chen, J., Zhou, X., Chen, D. Y., Zhao, R., ...Wang, J. G. & Chu, X. (2025). Transcriptome Profiling of the Primary and Crown Root in Response to Nitrate in Foxtail Millet (Setaria italica). Journal of Plant Growth Regulation, 44(9), 5023-5027.

11. Sun, M., Chen, Y., Chen, D. Y., Yang, Y., Zhao, M., Li, Y., ...Wang, J. G. & Yuan, X. (2025). Genome-wide identification and expression analysis of the SiSWEET gene family in Setaria italica and functional characterization of the SiSWEET13a in Arabidopsis. Plant Physiology and Biochemistry, 227, 110172.

12. Li, Z. D., Yao, X. L., Zhang, L., Zhang, J., Hao, J. H., Wu, H., ... Wang, J. G.& Wu, Y. (2025). Transcriptome profiling reveals abnormal cell wall components in the cleistogamy mutant 1 (clm1) lodicule of foxtail millet. Planta, 262(1), 2.

13. Hao, J. H., Kang, X., Zhang, L., Chen, J., Wang, D., Dong, S., ... & Wang, J. G. (2025). CRISPR/Cas9‐Mediated SiEPF2 Mutagenesis Attenuates Drought Tolerance and Yield in Foxtail Millet (Setaria italica). Plant, Cell & Environment, 48(8), 6043-6046.

14. Gao, L., Zhu, Q., Li, H., Wang, S., Fan, J., Wang, T., ... Wang, J. G. & Yang, G. (2025). Construction of a genetic linkage map and QTL mapping of the agronomic traits in Foxtail millet (Setaria italica). BMC genomics, 26(1), 152.

15. Wang, D., Su, M., Hao, J. H., Li, Z. D., Dong, S., Yuan, X., ...Wang, J. G. & Du, H. (2025). Genome-wide identification of the adaptor protein complexes and its expression patterns analysis in foxtail millet (Setaria italica L.). BMC Plant Biology, 25(1), 7.

16. Li, Y., Sun, M., Zhao, R., Chen, J., Chen, Y., Dong, S., ... & Wang, J. G. (2025). SiDWARF4 encodes an ent-copalyl diphosphate synthase (CPS) required for gibberellin biosynthesis and morphogenesis in foxtail millet. Journal of Integrative Agriculture, 24(6), 2438-2442.

17. Hao, J., Kang, X., Zhang, L., Zhang, J., Wu, H., Li, Z., ... & Wang, J. G. (2025). SiEPFs enhance water use efficiency and drought tolerance by regulating stomatal density in foxtail millet (Setaria italica). Journal of Integrative Agriculture, 24(2), 786-789.

18. Chen, D. Y., Su, M., Wu, H., Zhao, R., Wang, D., Dong, S., ... & Wang, J. G. (2024). Transcriptome profiling of foxtail millet (Setaria italica) pollen and anther. BMC Plant Biology, 24(1), 1221.

19. Yao, X. L., Li, Z. D., Zhang, M. H., Meng, H. X., Wang, Y. Z., Dong, S., ... & Wang, J. G. (2024). Transcriptomic analysis of hub genes regulating nitrate and glucose response of nitrate response deficiency 1 (NRD1) mutant in foxtail millet. Plant Cell Reports, 43(12), 289.

20. Sun, M., Li, Y., Chen, Y., Chen, D. Y., Wang, H., Ren, J., ... Wang, J. G. & Yuan, X. (2024). Combined transcriptome and physiological analysis reveals exogenous sucrose enhances photosynthesis and source capacity in foxtail millet. Plant Physiology and Biochemistry, 216, 109189.

21. Yao, X. L., Wang, Y. Z., Meng, H. X., Zhang, M. H., Zhou, X., Kang, X. T., ... & Wang, J. G. (2024). Identification of systemic nitrogen signaling in foxtail millet (Setaria italica) roots based on split-root system and transcriptome analysis. Plant Cell Reports, 43(10), 243.

22. Meng, R., Li, Z., Kang, X., Zhang, Y., Wang, Y., Ma, Y., ... & Wang, J. G. (2024). High overexpression of SiAAP9 leads to growth inhibition and protein ectopic localization in transgenic Arabidopsis. International Journal of Molecular Sciences, 25(11), 5840.

23. Meng, H. X., Wang, Y. Z., Yao, X. L., Xie, X. R., Dong, S., Yuan, X., ... & Wang, J. G. (2024). Reactive oxygen species (ROS) modulate nitrogen signaling using temporal transcriptome analysis in foxtail millet. Plant Molecular Biology, 114(3), 37.

24. Su, M., Wang, D., Li, Z. D., Hao, J. H., Dong, S., Yuan, X., ... & Wang, J. G. (2024). Establishment of in vitro pollen germination system in C4 model plant Foxtail Millet. Plant Cell, Tissue and Organ Culture (PCTOC), 156(3), 98.

25. Wang, D., Su, M., Hao, J. H., Li, Z. D., Dong, S., Yuan, X., ... & Wang, J. G. (2023). Dynamic transcriptome landscape of foxtail millet grain development. Seed Biology, 2(1).

26. Chu, X., Wang, J. G., Li, M., Zhang, S., Gao, Y., Fan, M., ... & Bai, M. Y. (2021). HBI transcription factor-mediated ROS homeostasis regulates nitrate signal transduction. The Plant Cell, 33(9), 3004-3021.

27. Chu, X., Li, M., Zhang, S., Fan, M., Han, C., Xiang, F., ... Wang, J. G. & Bai, M. Y. (2021). HBI1‐TCP20 interaction positively regulates the CEPs‐mediated systemic nitrate acquisition. Journal of Integrative Plant Biology, 63(5), 902-912.

28. Zhang, Q. Q., Wang, J. G., Wang, L. Y., Wang, J. F., Wang, Q., Yu, P., ... & Fan, M. (2020). Gibberellin repression of axillary bud formation in Arabidopsis by modulation of DELLA‐SPL9 complex activity. Journal of Integrative Plant Biology, 62(4), 421-432.

29. Feng, C., Wang, J. G., Liu, H. H., Li, S., & Zhang, Y. (2017). Arabidopsis adaptor protein 1G is critical for pollen development. Journal of integrative plant biology, 59(9), 594-599.

30. Wang, J. G., Feng, C., Liu, H. H., Feng, Q. N., Li, S., & Zhang, Y. (2017). AP1G mediates vacuolar acidification during synergid-controlled pollen tube reception. Proceedings of the National Academy of Sciences, 114(24), E4877-E4883.

31. Wang, J. G., Feng, C., Liu, H. H., Ge, F. R., Li, S., Li, H. J., & Zhang, Y. (2016). HAPLESS13-mediated trafficking of STRUBBELIG is critical for ovule development in Arabidopsis. PLoS Genetics, 12(8), e1006269.

32. Zhao, X. Y., Wang, J. G., Song, S. J., Wang, Q., Kang, H., Zhang, Y., & Li, S. (2016). Precocious leaf senescence by functional loss of PROTEIN S-ACYL TRANSFERASE14 involves the NPR1-dependent salicylic acid signaling. Scientific reports, 6(1), 20309.

33. Wang, J. G., Li, S., Zhao, X. Y., Zhou, L. Z., Huang, G. Q., Feng, C., & Zhang, Y. (2013). HAPLESS13, the Arabidopsis µ1 adaptin, is essential for protein sorting at the trans-Golgi network/early endosome. Plant Physiology, 162(4), 1897-1910.

七、专著教材

八、成果专利规程

专利

1.谷子基因Seita.8G189900和Seita.8G190200在控制醇溶蛋白品质中的应用，ZL20251 0418974.X，王家刚;赵蕊;褚晓茜;杨光辉;高路路。

九、荣誉奖励

1. 植物雌雄配子体发育的分子调控机制，2020年度山东省科学技术奖二等奖（第三完成人）；

2. 适配蛋白复合体调控植物有性生殖的分子机制研究，2019年度山东省高等学校科学技术奖叁等奖（第二完成人）；

3. 获得2017年度山东省优秀博士毕业论文奖。